The Buffalo Bills’ Wild Card victory was marred by the loss of the rookie running back, who was injured in the second half.

The Buffalo Bills may be missing one of their youngest contributors as their postseason run continues.

According to NFL Network’s Mike Garafolo, there’s fear within the organization that rookie running back Zack Moss may miss significant time with an ankle injury sustained during Saturday’s victory in the AFC Wild Card playoffs. Moss put up 47 yards (21 rushing, 26 receiving) before leaving due to an ankle injury. Dr. Matthew Provencher, the injury analyst for Fox Sports’ NFL coverage, had a slightly more optimistic outlook, forecasting that Moss could return in time for a possible appearance in the conference title game should take victory in their Divisional round contest next weekend.

Moss, 23, was chosen in the third round (86th overall) in April’s draft out of Utah. He would split the top rushing duties with Devin Singletary, tallying 481 yards and four scores on the ground. Moss also established himself as a short-yardage receiving threat of the backfield with 95 yards on 14 receptions, one of which went for a touchdown. Overall, 35 of Moss’ 126 touches went for first downs.

With Moss out, the Bills will likely rely on Singletary in the run game, and could potentially use one of their reserve rushers in an expanded role, including T.J. Yeldon or Taiwan Jones. Antonio Williams, who has been on and off the Bills’ practice squad all season, could likewise be an option after he scored two touchdowns in his NFL debut in the Week 17 regular season finale against Miami.

With their 27-24 win over Indianapolis on Saturday, Buffalo (14-3) will now await the results of Sunday’s action to see who they’ll host in the Divisional round. They will take on the highest-remaining seed from the Wild Card aftermath, which puts any team except seventh-seed Cleveland on the table.

Geoff Magliocchetti is on Twitter @GeoffJMags